Proteína 15-PGDH

SAÚDE Imagem: Canva Pro Tratamento experimental estimula células a produzir cartilagem funcional

[{"selector":"#anim-650f5ef0-f539-457d-8423-90112eec1126 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(0%, 0, 0) translate(25%, 0%) scale(1.5)","translate3d(0%, 0, 0) translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"fill":"forwards"}] [{"selector":"#anim-b2952471-66c5-41b5-a8df-1e0d0ab268d0","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-637de45e-1a9f-4ee1-bf9a-41ce1eee99f4","keyframes":{"transform":["translate3d(-116.38226%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] A osteoartrite causa dor crônica e limita movimentos. Até hoje, os tratamentos aliviam só sintomas. Imagem: Canva Pro

[{"selector":"#anim-a6ccf52b-61ba-452b-9dde-2454d11dc847 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(0%, 0, 0) translate(25%, 0%) scale(1.5)","translate3d(0%, 0, 0) translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"fill":"forwards"}] [{"selector":"#anim-e1ff5eaa-e05d-49f6-8247-4551e03252df","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-cdb1a51a-0068-4f57-ae7b-80ef517a975e","keyframes":{"transform":["translate3d(-116.38226%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Cirurgias são usadas em casos avançados. Mas um estudo recente pode mudar essa realidade. Imagem: Canva Pro

[{"selector":"#anim-3b256569-b7fd-429f-9d23-ade7173ab67b [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(0%, 0, 0) translate(25%, 0%) scale(1.5)","translate3d(0%, 0, 0) translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"fill":"forwards"}] [{"selector":"#anim-1a4f3284-0aca-45e3-a136-9999b2797a87","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-723837be-51c2-45dd-896f-28ac11974f4a","keyframes":{"transform":["translate3d(-116.38226%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Pesquisadores descobriram que bloquear a proteína 15-PGDH ajuda a regenerar cartilagem envelhecida. Imagem: Canva Pro

[{"selector":"#anim-2e5afeca-a948-4f59-8f16-5eefd20de038 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(0%, 0, 0) translate(25%, 0%) scale(1.5)","translate3d(0%, 0, 0) translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"fill":"forwards"}] [{"selector":"#anim-3bc3a861-4708-4fea-9b06-1f37b30a62ed","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a154b4e8-f56e-48a6-8a74-08a38bcd081e","keyframes":{"transform":["translate3d(-116.38226%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Essa proteína aumenta com a idade e contribui para inflamação, desgaste e perda de colágeno. Imagem: Canva Pro

[{"selector":"#anim-4bbe2f8a-f37b-4b14-a259-9015b8449477 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(0%, 0, 0) translate(25%, 0%) scale(1.5)","translate3d(0%, 0, 0) translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"fill":"forwards"}] [{"selector":"#anim-bfae8760-a76b-4ea2-9f90-2b8720e365a4","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4aed7bef-e5fe-45b0-a1b9-355432abca8e","keyframes":{"transform":["translate3d(-116.38226%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Surpreendentemente, a regeneração ocorre sem células-tronco, apenas reprogramando condrócitos. Imagem: Canva Pro

[{"selector":"#anim-d3eed19e-b814-4280-99f1-ff54bf0f3b70 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(0%, 0, 0) translate(25%, 0%) scale(1.5)","translate3d(0%, 0, 0) translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"fill":"forwards"}] [{"selector":"#anim-61e8d8d4-c389-48ce-abf4-7680e760abc6","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-938806df-093d-4d46-9118-6a2a15d9a121","keyframes":{"transform":["translate3d(-116.38226%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] As células voltam a produzir cartilagem hialina, resistente e essencial para o deslizamento das juntas. Imagem: Canva Pro

[{"selector":"#anim-d889c29a-6367-45e5-9272-9273f5115655 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(0%, 0, 0) translate(25%, 0%) scale(1.5)","translate3d(0%, 0, 0) translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"fill":"forwards"}] [{"selector":"#anim-7476d7c6-2628-4c2d-ab35-657df2226ecc","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-cce2aa6e-4696-4832-840e-14bb68c029b5","keyframes":{"transform":["translate3d(-116.38226%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] O tratamento também protege contra artrite após lesões, reduzindo inflamação e melhorando mobilidade. Imagem: Canva Pro

[{"selector":"#anim-ce641d97-7ad6-4280-8fc4-f2d9f8c2a95d","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1535925f-549a-4f26-8826-ba1409d15fc4","keyframes":{"transform":["translate3d(-116.38226%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Mesmo em cartilagem humana removida em cirurgias, o bloqueio da 15-PGDH iniciou regeneração. Imagem: Canva Pro

[{"selector":"#anim-1f3f555c-2b22-4bea-b6d1-a3d5fb56a37b [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(0%, 0, 0) translate(25%, 0%) scale(1.5)","translate3d(0%, 0, 0) translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"fill":"forwards"}] [{"selector":"#anim-4c999ec9-4c8d-4620-81df-6983c94d773d","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d8620247-3b2c-4b6e-aabf-97eb55e74f7f","keyframes":{"transform":["translate3d(-116.38226%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Futuras terapias podem adiar ou até evitar próteses, com injeções ou medicamentos orais. Imagem: Canva Pro

[{"selector":"#anim-ce17ea72-d21f-4ef9-939b-8745cfd37e9f [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(0%, 0, 0) translate(25%, 0%) scale(1.5)","translate3d(0%, 0, 0) translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"fill":"forwards"}] [{"selector":"#anim-b9c0de02-24cd-448e-92fc-5d9a5bac3337","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-82582818-7b32-4377-b5ce-b2397157322f","keyframes":{"transform":["translate3d(-120.13652%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Essa técnica ainda é experimental, mas os resultados prometem revolucionar a osteoartrite. Saiba mais! Imagem: Canva Pro Leia mais